Now showing items 691-710 of 1298
Cuscó Pons, Pol (Date of defense: 2017-12-13)
Des de l’aparició de les tecnologies de seqüenciació d’alt rendiment, els conjunts de dades biològiques han esdevingut cada cop més grans i complexes, la qual cosa els fa pràcticament impossibles d’interpretar manualment. ...
Jiménez Luna, José (Date of defense: 2019-10-24)
Deep learning approaches have become increasingly popular in the last years thanks to their state-of the-art performance in fields such as computer vision and natural language understanding. The first goal of this thesis ...
Hong, Xiaotong (Date of defense: 2022-10-06)
La regeneración del músculo esquelético depende de la expansión correcta de las células madre inactivas residentes (células satélite), un proceso que se vuelve menos eficiente con el envejecimiento, por razones en gran ...
Torrens Fontanals, Mariona (Date of defense: 2022-02-11)
Molecular dynamics (MD) simulations are a well-established technique to characterize the structural motions of biological systems at atomic resolution. However, accessing, viewing, and sharing MD trajectories is typically ...
Tur Mongé, Inma (Date of defense: 2014-05-12)
Expression quantitative trait loci (eQTL) mapping constitutes a challenging problem due to the high-dimensional multivariate nature of continuous gene expression traits and discrete genotypes from genetical genomics ...
Villar Vinuesa, Rocío (Date of defense: 2019-02-20)
Introducción: La protección social a las trabajadoras embarazadas comprende la incapacidad temporal por contingencia común (ITcc) y la prestación por riesgo durante el embarazo y/o la lactancia (PRE). Objetivos: 1) Examinar ...
Gómez Escoda, Blanca (Date of defense: 2010-11-26)
When DNA replication is challenged, cells activate a DNA synthesis checkpoint blocking cell cycle progression until they are able to overcome the replication defects. In fission yeast, Cds1 is the effector kinase of this ...
Yubero Lahoz, Samanta (Date of defense: 2013-11-18)
3,4-methylenedioxymethamphetamine (MDMA, ecstasy) is one of the most abused recreational drugs in the world. It has been extensively reported that this drug inhibits its own metabolism by inhibiting a polymorphic liver ...
Batlle Garcia, Jordi de (Date of defense: 2011-05-09)
Background and objectives: Recent research has shown an association between a healthy diet and reduced chronic obstructive pulmonary disease (COPD) incidence. However, the potential role of diet in COPD prognosis is ...
Fares, Hani (Date of defense: 2022-07-05)
Refugees and asylum-seekers often encounter situations in which their health and well-being are compromised. Despite their health needs, access to healthcare is often restricted in host countries, and this is aggravated ...
Garin Boronat, Olatz (Date of defense: 2013-03-15)
L’objectiu global d’aquesta tesis doctoral va ser identificar les fortaleses i limitacions de les mesures de Qualitat de Vida Relacionada amb la Salut desenvolupades específicament per pacients amb insuficiència cardíaca. ...
Oswal, Natasha Nikhil (Date of defense: 2023-06-08)
El envejecimiento implica un aumento de la fragilidad en función del tiempo que resulta en la aceleración de la mortalidad. Para comprender el papel temporal de varias proteínas en el envejecimiento, utilizamos el sistema ...
Agustí Benito, Cristina (Date of defense: 2007-05-28)
La transició Epiteli-Mesènquima es dóna durant el desenvolupament embrionari i en els estadis tardans de la progressió tumoral permetent que es produeixi la metàstasi. Aquestes transicions necessiten una repressió de ...
Domínguez Solà, David (Date of defense: 2003-04-03)
Els factors de transcripció de la família Snail són fonamentals en la "transició epiteli-mesènquima", procés morfogènic essencial en el desenvolupament embrionari i en els fenòmens metastàsics tumorals.<br/>En els mamífers ...
Mercader Bigas, Josep Maria (Date of defense: 2008-07-11)
Els trastorns de la conducta alimentària (TCA) tenen una etiologia complexa en la que hi intervenen factors de predisposició socioculturals, ambientals i genètics. S'ha aprofundit en les bases moleculars dels TCA mitjançant ...
Tolosa Ramon, Queralt (Date of defense: 2023-07-26)
The outer epithelial layer is the first cell type that emerges during development, providing essential mechanical protection and is indispensable for morphogenesis. Here, we study how the interplay between molecular and ...
Pezzano, Fabio (Date of defense: 2022-06-13)
Cells commonly live in a crowded environment, in a tissue or in a developing embryo. The extracellular matrix and/or surrounding neighboring cells can impose physical deformations to which cells need to adapt in order to ...
Kłosin, Adam (Date of defense: 2015-11-09)
Desde Darwin y Lamarck, a los biólogos les ha intrigado la posibilidad de que rasgos adquiridos debido al ambiente pudieran ser heredados. Se han descrito muchos ejemplos de este tipo debidos a perturbaciones del ambiente ...
Scrofani, Jacopo (Date of defense: 2014-10-10)
During mitosis, spindle assembly involves different sources of microtubules including centrosomes and chromosomes. While the role of centrosomes has been extensively studied, we still do not fully understand how chromosomes ...
Macías Ribela, Sara (Date of defense: 2008-06-13)
The mechanisms of pre-mRNA splicing regulation are poorly understood. Here we dissect how the Saccharomyces cerevisiae ribosomal L30 protein blocks splicing of its pre-mRNA upon binding a kink-turn structure including the ...