Now showing items 870-889 of 1296
Escrich Montañana, Ainoa (Date of defense: 2022-12-01)
The emergency to obtain effective substances against cancer, and the awareness to protect natural resources make plant biofactories a promising alternative for obtaining plant-derived compounds. In this context, the ...
Gelabert Xirinachs, Pere (Date of defense: 2018-12-14)
La malària és una malaltia infecciosa causada per diverses espècies de protozous del gènere Plasmodium, capaces d’infectar eritròcits humans. La malària és probablement la patologia infecciosa que ha causat més morts al ...
Pinho, Andreia V. (Date of defense: 2011-07-14)
Pancreatic acinar cells display plasticity to acquire distinct differentiation programs, being involved in diseases as chronic pancreatitis and pancreatic ductal adenocarcinoma. This work shows that acinar cells cultured ...
Vivancos Prellezo, Ana (Date of defense: 2006-06-02)
La vida aeróbica conlleva la formación de especies reactivas derivadas del oxígeno: el radical hidroxilo (OH·), el ión superóxido (O2·-) y el peróxido de hidrógeno (H2O2). En Schizosaccharomyces pombe, dos rutas controlan ...
Aguilar Izquierdo, Susana (Date of defense: 2004-02-26)
Exocrine pancreatic cancer is the fifth leading cause of death from malignant disease in Western society and it is one of the most aggressive human tumors. Once diagnosed, the 12-month patient survival is less than 5%. ...
Loubat Casanovas, Jordina (Date of defense: 2015-06-12)
García Parra, Jetzabel (Date of defense: 2012-06-21)
Breast cancer is the main cause of cancer death in women. Improved treatments, prevention programs and earlier detection are reducing the rate of death; however, there is still a high percentage of mortality by this cancer. ...
Ollé Espluga, Laia (Date of defense: 2015-10-15)
This dissertation aims to describe the main processes leading to interaction between safety representatives and workers and the factors influencing it, as well as analysing its effects. Adopting a multi-method approach, ...
Aso Pérez, Ester (Date of defense: 2008-12-19)
Los trastornos emocionales de tipo depresivo y la ansiedad son las formas más prevalentes de enfermedad mental y suponen un serio problema de salud en la sociedad occidental. Recientemente, se ha postulado que el sistema ...
Castañé Forn, Anna (Date of defense: 2005-06-16)
Con la finalidad de explorar con profundidad las bases neurobiológicas de la adicción a cannabinoides hemos llevado a cabo diferentes estudios farmacológicos y moleculares. El sustrato neuroanatómico de la dependencia ...
Galeote González, Lola (Date of defense: 2008-12-12)
El tabaquismo es una enfermedad crónica y recurrente caracterizada por la necesidad imperiosa o compulsiva de consumir nicotina para experimentar la sensación de placer característica de su uso, a pesar de las consecuencias ...
Nadal i Roura, Xavier (Date of defense: 2011-09-23)
This work is focused in the study of the pathophysiology of neuropathic pain, particularly in the role of the endogenous opioid and cannabinoid systems. Neuropathic pain is a chronic illness with a high prevalence in the ...
Ocaña Pallarès, Eduard (Date of defense: 2020-01-23)
La present tesi doctoral se centra, d’una banda, en reconstruir l’evolució de famílies gèniques potencialment relacionades amb determinats events de convergència evolutiva en eucariotes; i d’altra banda, en desenvolupar ...
Picón Pagès, Pol (Date of defense: 2022-09-09)
Society increase in live expectancy will cause a rise in Alzheimer’s Disease (AD) diagnosis, thus, there is a need to further understand how it works. One of the main culprits of this disease amyloid-β peptide (Aβ), this ...
Miñana Gómez, Belén (Date of defense: 2008-03-06)
Para avanzar en el entendimiento de las vías de señalización moleculares involucradas en la progresión de cáncer tumoral, se construyo una plataforma personalizada de cDNAs, la cual contiene genes de vías de señalización ...
Hänzelmann, Sonja (Date of defense: 2012-10-11)
In the last decade, molecular biology has expanded from a reductionist view to a systems-wide view that tries to unravel the complex interactions of cellular components. Owing to the emergence of high-throughput technology ...
Benítez Arciniega, Alejandra Donají (Date of defense: 2014-02-10)
La identificación de los factores de riesgo de la obesidad es una prioridad en la investigación en salud. El peso específico de la dieta y de sus componentes favorece o retrasa el desarrollo de la obesidad. La obesidad es ...
Tejero Cicuéndez, Héctor (Date of defense: 2021-12-10)
Biodiversity patterns result from the interplay of evolutionary, ecological, and environmental processes. Investigating the drivers of such patterns is central to evolutionary biology, and it is further essential to ...
Garí de Barbarà, Mercè (Date of defense: 2013-04-15)
The present research explores the levels and patterns of accumulation of a wide range of persistent organic pollutants (POPs) in the human population. It assesses two major families of POPs, namely organochlorine compounds ...
Peligero Cruz, Cristina (Date of defense: 2015-11-17)
Bloquejar la via PD-1/PD-L1 ha sorgit com una estratègia prometedora per a restaurar la resposta immune efectora en individus infectats amb el virus de la immunodeficiència humana (VIH). Malgrat l’extensa recerca duta a ...