Blevins, William Robert (Date of defense: 2020-01-17)
All living organisms respond to environmental stimuli by modulating the activity of different genes. This response can occur across many locations throughout the cell such as at the level of transcription, ...
Calvo Arnedo, María Isabel (Date of defense: 2012-12-21)
En el laboratorio se utiliza como sistema modelo la levadura Schizosaccaromyces pombe para poder estudiar la respuesta a estrés oxidativo. Las dos rutas principales de respuesta a estrés oxidativo son ...
Paulo Mirasol, Esther (Date of defense: 2014-12-19)
Reactive oxygen species (ROS) are a variety of molecules derived from molecular oxygen during different metabolic processes. ROS can react with different cellular components resulting in lipid peroxidation, ...
Iannone, Camilla (Date of defense: 2014-05-23)
Intron removal is a necessary step for expression of most genes in higher eukaryotes, and alternative splice selection is a highly regulated mechanism that endows a single gene with the possibility to ...
Benisty, Hannah (Date of defense: 2019-12-13)
The RAS oncogenes KRAS, NRAS and HRAS are mutated in one third of human cancers where they exhibit different mutation patterns. A potential factor contributing to this mutation bias is the variation ...
García Santamarina, Sarela (Date of defense: 2013-06-14)
Oxidation of specific cysteines in proteins by hydrogen peroxide (H2O2) is a cellular mechanism that triggers signalling pathways, such as the antioxidant responses in microbial systems. However, H2O2 ...
Castillo Andreo, Esther (Date of defense: 2005-06-17)
Las especies reactivas del oxígeno (ROS), superóxido (O2o-), peróxido de hidrógeno (H2O2), y radical hidroxilo (OHo), se generan a partir de la reducción parcial del oxígeno molecular durante procesos ...
Baltzis, Athanasios (Date of defense: 2023-03-20)
Recent advances in deep learning techniques have revolutionised protein structure modelling. Since AlphaFold2’s release, a set of tools have now become available to predict native-like structures at ...
Salichs Fradera, Eulàlia (Date of defense: 2008-12-15)
PolyHistidine repeats and DYRK1A: from the localization to the function<br/>El principal objectiu d'aquesta tesi ha estat el d'esbrinar noves funcions de la proteína quinasa DYRK1A en el nucli cel.lular. ...
Padró i Jové, Mercè (Date of defense: 2011-03-28)
Alterations in the expression of carbohydrates and the enzymes involved in their synthesis (glycosidases and glycosyltransferases) can be considered as universal feature of malignant transformation. ...