Mostrando ítems 1-9 de 9
Galán i Palma, Luis (Fecha de defensa: 2023-03-22)
Pluripotent stem cells (PSCs) have the ability to self-renew and give rise to almost every somatic cell type. Because of their enormous potential as a tool for regenerative medicine, understanding ...
Santanach Buxaderas, Alexandra (Fecha de defensa: 2016-10-28)
Polycomb group (PcG) proteins are transcriptional repressors that control cell identity and development. In mammals, at least five different Cbx prorteins are believed to associate with the core Polycomb ...
Vivori, Claudia (Fecha de defensa: 2019-02-14)
Alternative splicing (AS) is a mechanism of post-transcriptional regulation that plays an important role during development and in the maintenance of stem cell pluripotency. The dynamics of AS ...
Aulicino, Francesco (Fecha de defensa: 2016-12-15)
The adaptive response of cells to external stimuli is an intriguing mechanism at the basis of the existence of life itself. For this purpose, signalling pathways and gene regulatory networks elegantly ...
Plana Carmona, Marcos (Fecha de defensa: 2021-03-17)
Continuous C/EBPa expression converts B cells into macrophages while its transient upregulation before the Yamanaka factors yields highly efficient iPSC reprogramming. C/EBP members regulate Il6 ...
Tu, Xiaochuan (Fecha de defensa: 2023-07-27)
Embryonic stem cells (ESCs) are derived from the inner cell mass of the pre-implantation embryo and can recapitulate early developmental stages of the embryo. ESCs have the ability to continuously ...
Alcaine Colet, Anna (Fecha de defensa: 2019-11-04)
The self-renewing nature of embryonic stem cells (ESCs) is a consequence of their ability to proliferate while maintaining pluripotency, by means the capacity to differentiate into all adult cell types. ...
Martinez Sarmiento, Jose Angel (Fecha de defensa: 2023-05-04)
Elucidating the mechanism of somatic cell reprogramming has been hampered by the limitations of iPSC systems to uncover the correctly reprogramming cells. Here, by using the highly efficient heterokaryon ...
Cortés Albarracín, Paola Andrea (Fecha de defensa: 2019-12-02)
Mouse embryonic stem cells (ESCs) require extracellular signals to induce the expression of intrinsic core pluripotency factors: Oct4, Sox2 and Nanog, known as the OSN triad. Notably, the Wnt/β-catenin ...