Now showing items 1-20 of 42
Llurda Almuzara, Luis (Date of defense: 2022-07-12)
La lesión de ligamento cruzado anterior es una de las lesiones más devastadoras en el ámbito deportivo. El valgo dinámico de rodilla durante el gesto deportivo puede ser uno de los mecanismos más comunes en la lesión del ...
Bosch Canals, Begoña María (Date of defense: 2019-07-16)
Nowadays, there are approximately 10 million people worldwide with visual impairment due to corneal diseases. Currently, the main therapeutic solution is the transplant of a donor's cornea. The great majority of transplants ...
Bállega Moreno, Elisabet (Date of defense: 2017-07-11)
Saccharomyces cerevisiae és un microorganisme unicel·lular eucariota que per presentar el seu genoma totalment seqüenciat, gran facilitat de manipulació en el treball de laboratori, ja que molts dels seus gens es troben ...
Quandt Herrera, Eva (Date of defense: 2017-11-16)
La desregulación en los mecanismos de control del ciclo celular es un evento indiscutiblemente asociado a la aparición de diversas patologías, entre las que destacan los procesos tumorales. Como principales reguladores del ...
Ricco Pacheco, Natalia (Date of defense: 2013-07-23)
La ciclina Cln3 es un activador crítico de START, cuya sobreexpresión provoca células de menor tamaño que progresan rápidamente por el ciclo celular, mientras que su deleción induce un mayor tamaño de las células y retrasa ...
Carballar Ruiz, María de los Reyes (Date of defense: 2021-02-25)
DNA double-strand breaks (DSBs) are considered the most deleterious lesions of DNA and they are repaired by means of two main mechanisms: homologous recombination (HR) and non-homologous endjoining (NHEJ). These mechanisms ...
Hernández Ortega, Sara (Date of defense: 2014-07-18)
El control del ciclo celular está altamente regulado mediante diferentes CDKs asociadas a ciclinas. En Saccharomyces cerevisiae, la CDK esencial Cdc28 es la que regula mayoritariamente este proceso. En la fase G1 del ciclo ...
Miralpeix Monclús, Cristina (Date of defense: 2019-12-04)
Obesity prevalence in worldwide population is increasing every day due to an imbalance between the energy intake and the energy expenditure. Rich-caloric food is highly palatable and easily accessible, whereas sedentary ...
Fosch Masllovet, Anna (Date of defense: 2022-07-28)
Obesity has become a pandemic disease in the last 40 years. The WHO estimates that the population with overweight has nearly tripled since 1975, and the tendency is still growing. These data have an impact on health and ...
Casas Prat, María (Date of defense: 2019-11-18)
Carnitine palmitoyltransferase 1C (CPT1C) is the brain-specific isoform of the CPT1 family which is located at the endoplasmic reticulum (ER) of neurons and exhibits low catalytic activity, but still maintains the capacity ...
Bru Rullo, Samuel (Date of defense: 2015-07-20)
Throughout its lifespan, eukaryotic cells steadily consume free cytoplasmic orthophosphate to produce phospholipids and mRNA. However, during DNA synthesis, in a matter of minutes, cells require large amount of phosphate ...
Masip Sales, Núria (Date of defense: 2022-01-27)
Fa quasi 40 anys del descobriment de les ciclines, les proteïnes oscil·lants tradicionalment dividies en dos grups, “cicle cel·lular” i “ciclines transcripcionals”, que duen a terme els seus rols juntament amb la seva ...
Lidón Moyano, Cristina (Date of defense: 2017-10-06)
In Spain, two smoke-free laws have been passed after the approval of the FCTC. In 2005, it came into effect a smoke-free legislation (Law 28/2005). This law was a great advance for public health in Spain; however, it was ...
Navarro Martínez, Lourdes (Date of defense: 2017-09-29)
Las proteínas TCF7L2 (transcription factor 7-like 2) son un conjunto de factores de transcripción que participan en la vía Wnt y son responsables, entre otras funciones, del mantenimiento de las células madre y la formación ...
Lamarca Dams, Aloa (Date of defense: 2013-09-13)
Peripheral neuropaties are one of the major complications of the Peripheral Nervous System. Depsite the big importance of those pathologies, less drugs are effective for their treatment, and most of the prescribed drugs ...
Díez Deustua, Patricia (Date of defense: 2015-12-02)
En el presente trabajo revisamos las diferentes variables que han sido asociadas al perdón. Son muchos los factores que influyen en que dicho proceso se lleve a cabo o no. Estudios previos han analizado la importancia ...
Pérez Paredes, Alexis E. (Date of defense: 2022-07-22)
The cell cycle is regulated at different layers of control in either homeostatic or non-homeostatic conditions. Hence, in this work we analyse how time and stress modulate the cell cycle through the activity of the G1 ...
Ramírez Flores, Sara (Date of defense: 2014-07-18)
Recent data suggest that ghrelin exerts its orexigenic action through regulation of hypothalamic AMP-activated protein kinase pathway, leading to a decline in malonyl-CoA levels and desinhibition of carnitine palmitoyltransferase ...
Gámiz Sanfeliu, María (Date of defense: 2017-07-11)
Forgiveness is a human strength mainly helpful for the wellbeing of social relationships. Research has showed the potential benefits of forgiving for physical and mental health as well as for restoring relationships. As a ...
Celma Nos, Ferran (Date of defense: 2022-05-17)
Iron is a biometal involved in many physiological processes essential for life. Regulation of both systemic and cellular iron homeostasis is crucial for health. The IRP/IRE post-transcriptional regulatory system is in ...