Fibroblast role in the acquisition and maintenance of breast cancer resistance to anti-HER2 therapies. Identification of novel compensatory tyrosine kinase receptors 

Fernández Noguera, Patricia (Date of defense: 2016-02-04)

HER2 positivity defines a molecular subtype of breast cancer with an aggressive biological behaviour and poor prognosis. Its pharmacological targeting with the monoclonal antibody Trastuzumab, and later on with the small ...