Universitat de Barcelona
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Los gabapentinoides son una familia de fármacos que se unen con gran afinidad a la subunidad α2δ-1 de los canales de calcio voltaje-dependientes (VGCCs). Fármacos de esta familia como la pregabalina o la gabapentina se ...
[eng] Psychosis is a mental health problem characterized by a loss of contact with reality, which is considered the defining feature of schizophrenia spectrum disorders. However, psychotic symptoms may occur in other medical ...
L’Esclerosi Lateral Amiotròfica (ELA o ALS) és una malaltia neuromuscular caracteritzada per la degeneració selectiva de les motoneurones (MN) superiors e inferiors del còrtex motor, el tronc de l’encèfal i la medul•la ...
Parkinson's disease (PD) is a neurodegenerative disorder characterized by movement impairment, or parkinsonism, for which there is still no cure. The manifest clinical signs result from neuronal loss of more ...
[eng] Parkinson’s disease (PD) is a chronic, incurable, progressive neurodegenerative disorder pathologically characterized by intracellular aggregates of α-synuclein (α-syn) forming Lewy bodies (LBs) and the loss of ...
[eng] Alzheimer's disease (AD), characterized by the loss of memory and other cognitive abilities, is the predominant form of dementia. Given the impact it has on individuals, affected families and health systems, it is ...
AMPA receptors (AMPARs) are responsible for the 90% of synaptic transmission and are involved in plasticity, developmental and neurological processes. Their function depends on the proteins interacting with the AMPAR ...
Desde que se establecen las sinapsis hasta que son plenamente maduras, experimentan diversos cambios. En el terminal presináptico, a nivel morfológico se produce un rellenado progresivo del número de vesículas sinápticas ...
Synapses are the contact sites where the transfer of information from the presynaptic to the postsynaptic site occurs. Correct processing of information requires that synapses continuously adapt their properties to an ...
Las enfermedades priónicas, también conocidas como EETs (Encefalopatías Espongiformes Transmisibles), son un grupo de enfermedades neurodegenerativas fatales que, debido a su transmisibilidad potencial han tenido un gran ...
