Now showing items 60-79 of 186

    Development of tunable bioinks to fabricate 3D-printed in vitro models: a special focus on skeletal muscle models with potential applications in metabolic alteration studies 

    García Lizarribar, Andrea (Date of defense: 2022-01-28)

    In vitro engineered three-dimensional tissue models are attracting an increasing interest due to their potential applications in preclinical assays. On the one hand, they are an alternative to the high costs, ethical issues ...

    Domain walls, primordial black holes and inflation 

    Sanglás Martín, Albert (Date of defense: 2023-10-10)

    [eng] This thesis investigates primordial black holes and their observational consequences. In the first part, we examine the behavior of domain walls produced during inflation, and their subsequent collapse, leading to ...

    Driven soft matter at the nanoscale 

    Granados Leyva, Sergio (Date of defense: 2024-05-06)

    [eng] This thesis will present a body of articles on the research topic of soft matter. Soft matter is a research subfield of condensed matter, where the energy required for deforming the media is comparable to that of ...

    Dynamic force spectroscopy and folding kinetics in molecular systems 

    Alemany i Arias, Anna (Date of defense: 2014-11-04)

    Codification of genetic information; regulation of gene expression; transport of nutrients inside cells; immune protection against infectious agents; transduction of external signals... These are some of the crucial processes ...

    Dynamical and Mechanical Characterisation of Bi- and Tri-dimensional Neuronal Cultures: from Health to Disease 

    Fernández López, Clara (Date of defense: 2024-01-12)

    [eng] In this PhD thesis, we leverage the well established foundations of complex systems physics and integrate insights from medicine and materials engineering to advance our understanding of neuroscience. Our primary ...

    Dynamics of Isotopically Pure He Droplets Doped with Atomic Impurities 

    Leal Martín, Antonio Jesús (Date of defense: 2016-07-05)

    Helium is the second lightest element and the second most abundant element in the universe. It is named for the Greek god of the sun, Helios, and it was first discovered by French astronomer Jules Janssen as an unknown ...

    Dynamics of nanoparticles in 3D tumor models 

    Olea, Rodica-Alis (Date of defense: 2024-01-15)

    [eng] In the last decades, great research effort was focused towards designing nanocarriers for cancer therapy. However, nanoparticle translation from basic research to the clininc has proven to be a challenging task, with ...

    Dynamics of the late-winter ENSO teleconnection to the North Atlantic-European region 

    Mezzina, Bianca (Date of defense: 2021-11-30)

    The El Niño-Southern Oscillation (ENSO) is a natural mode of climate variability in the tropical Pacific, which not only perturbs the local atmosphere, but whose impacts can also reach remote, extra-tropical regions through ...

    Efectos de la implantación iónica de boro sobre el aislamiento eléctrico entre MESFET's en circuitos integrados de GaAs 

    Samitier i Martí, Josep (Date of defense: 1986-06-25)

    Al principio de los años 60, aparecieron los primeros transistores FET en Arseniuro de Galio. En el instante en que el silicio se imponía de forma definitiva al germanio, la aparición de este nuevo material venía justificada ...

    Effective Dynamics of Black Hole Horizons 

    Licht, David (Date of defense: 2021-04-14)

    In this thesis we present a new aspect pertaining to the effective field theory of general relativity in the limit of a large number D of dimensions. We demonstrate that the theory initially developed to capture the physics ...

    Effects of substrate-derived cues in driving the selforganization of organoid-derived intestinal epithelia 

    Larrañaga Carricajo, Enara (Date of defense: 2021-05-25)

    Intestinal cells self-organize into 3-dimensional (3D) organoids that recapitulate the in vivo structural and functional characteristics when embedded in a 3D cell-derived protein mixture (Matrigel). However, these very ...

    El problema del confinament atacat des de l'acció efectiva de la Q. C. D. 

    Soto Riera, Joan (Date of defense: 1985-12-11)

    Aquesta memòria està estructurada en set capítols i vuit apèndixs. Dels capítols, els dos primers es poden considerar introducció, mentre que la resta són ja treball original. El capítol I està dedicat a una descripció ...

    Electrohydrodynamic jet printing: stability and reproducibility 

    Ramón Ferrer, Alberto (Date of defense: 2023-01-16)

    [eng] Additive manufacturing, also referred as 3D printing, is a layer-by-layer technique that allows producing three-dimensional objects directly from a digital model. It has enabled the fabrication of innovative products ...

    Energy Efficient Radio Resource Management for Heterogeneous Networks 

    Bastos, Joaquim Manuel Camões Sobral de (Date of defense: 2019-12-17)

    In the continuous evolution of mobile communication systems, there are many issues and aspects to be addressed, as well as in their effective implementation and deployment on cellular networks. In a general way, the most ...

    Energy Harvesting Solutions for Self-Powered Devices: From Structural Health Monitoring to Biomedical Applications 

    Álvarez-Carulla, Albert (Date of defense: 2021-01-29)

    The thesis reflects the research carried out on the development of truly self-powered devices. The development of devices for the scopes of Structural Health Monitoring (SHM) and Point-of-Care devices (PoC) is shown. New ...

    Engineered functional 3D spheroids for β-cell encapsulation 

    Clua Ferré, Laura (Date of defense: 2022-09-30)

    [eng] Type 1 Diabetes Mellitus (T1DM) is known to be associated with the immune-mediated destruction of insulin-secreting β-cells. Cell replacement therapy is thought to be a potential long-lasting cure for diabetes. In ...

    Engineered functional skeletal muscle tissues for in vitro studies 

    Fernández Garibay, Xiomara Gislen (Date of defense: 2021-11-26)

    The skeletal muscle is the largest tissue of the human body. Its main function is to generate contractile forces, essential for locomotion, thermogenesis, and metabolism. Fundamental research on skeletal muscle in health ...

    Engineering in vitro models of the intestinal mucosa to study the role of the stroma on the epithelium 

    Abad i Lázaro, Aina (Date of defense: 2023-07-20)

    [eng] The standard in vitro model of the small intestine in the field of drug development still consists in a monolayer of cancer-derived cells seeded on a hard substrate. Despite the huge advances that this model has ...

    Enhancing electrochemical performances of supercapacitors 

    Avireddy, Hemesh (Date of defense: 2019-07-11)

    The thesis is focused on the development and enhancement of the electrochemical properties of the carbon based supercapacitors and pseudocapacitors. To overcome the capacitance loss at the condition of fast charging in the ...

    Enzyme Powered Nanomotors Towards Biomedical Applications 

    Hortelão, Ana Cãndida (Date of defense: 2021-09-03)

    The advancements in nanotechnology enabled the development of new diagnostic tools and drug delivery systems based on nanosystems, which offer unique features such as large surface area to volume ratio, cargo loading ...