Ara mostrant els elements 10777-10796 de 11082

    Unravelling the Role of Long Noncoding RNAs in the Context of Cell-growth and Regeneration 

    Amador Rios, Raziel (Data de defensa: 2022-02-10)

    Long noncoding RNAs (lncRNAs) have proven biological roles in plethora cellular contexts. Nonetheless, only a handful have been clearly characterized, leaving thousands of newly discovered lncRNAs without an associated ...

    Unveiling novel components of the protein complex responsible for cGMP synthesis in retinal photoreceptors: role in cell physiology and disease 

    López Begines, Santiago (Data de defensa: 2016-11-18)

    In photoreceptor cells of the retina, light triggers a protein G-mediated enzymatic cascade that leads to hydrolysis of cGMP. The drop in cGMP levels causes the closure of cGMP-channel at the plasma membrane, decreasing ...

    Unveiling novel functions of the trascriptional repressor HDAC7 in B lymphocyte development 

    Azagra Rodríguez, Alba (Data de defensa: 2019-11-29)

    B lymphopoiesis is the result of several cell lineage choices and differentiation steps whose perturbation leads to B cell malignancies. Cellular transitions for B cell generation have been associated with gene activation ...

    Unveiling Protein-Substrate Interactions and Conformations that Influence Catalysis in Carbohydrate-Active Enzymes 

    Raich Armendáriz, Lluís Adrià (Data de defensa: 2018-06-14)

    Enzymes have attracted the attention of chemists and biologists since long ago due to their molecular complexity and tremendous efficiency. They are highly specific catalysts that make chemical reactions possible at mild ...

    Unveiling the biological role of stigmasterol biosynthesis in tomato plants 

    Gutiérrez García, Laura (Data de defensa: 2019-10-31)

    In plants, the sterol biosynthetic pathway leads to the production of a complex mixture of end-products, among which β-sitosterol, stigmasterol, campesterol, and cholesterol are the most abundant ones. Stigmasterol, the ...

    Unveiling the role of DXS-Interacting (DXI) proteins in the regulation of plastidial isoprenoid biosynthesis 

    Llamas Pámanes, Ernesto (Data de defensa: 2017-09-15)

    Chloroplasts provide plants with metabolic pathways that are unique among eu- karoytes, including the methylerythritol 4-phosphate pathway (MEP) for the pro- duction of isoprenoids essential for photosynthesis and plant ...

    Unveiling the role of Slc7a7 in hematopoiesis 

    Giroud-Gernetant Deus, Judith (Data de defensa: 2023-11-20)

    [eng] Lysinuric Protein Intolerance (LPI) is a rare autosomal recessive disorder caused by mutations in the SLC7A7 gene, which encodes the y+LAT1 transporter. LPI presents a pleiotropic phenotype that varies among patients, ...

    Unveiling the therapeutic potential of THC in endometrial cancer 

    Coll Iglesias, Laura (Data de defensa: 2022-11-23)

    [eng] Endometrial cancer represents the most common cancer arising from the uterine cavity and there is little hope for patients with recurrent or metastatic disease. Prior studies of our group reported autophagy pathway ...

    Unveiling viral structures by single-molecule localization microscopy 

    Arista Romero, Maria (Data de defensa: 2021-06-28)

    Influenza A virus is one of the most outstanding human viruses. The major treatments against influenza are small analogues, monoclonal antibodies and vaccines, however, due to the fast mutation of the seasonal influenza ...

    Urban Trajectories. A comparative study between Rio de Janeiro’s Favelas and Johannesburg’s Townships 

    Rocha Franco, Sérgio H. (Data de defensa: 2019-05-22)

    My general objective with this thesis is to contribute to the search for connections between postcolonial and critical understandings in urban studies. Building on my analysis of the urban trajectories of Rio de Janeiro’s ...

    Urban transport externalities 

    Pasidis, Ilias (Data de defensa: 2017-06-21)

    Chapter 2 of this dissertation estimates the joint causal effect of highway and railway Infrastructure on the suburbanization of population in European cities. Using a unique dataset of 579 European cities from 29 European ...

    Urbanisme i arquitectura a la Girona d'època moderna: XVI-XVIII 

    Carbonés Amagat, Anna (Data de defensa: 2016-01-28)

    Aquesta tesi és un estudi exhaustiu sobre la ciutat de Girona a partir de l'anàlisi dels diferents burgs o barris que la configuren. Aquestes unitats urbanístiques seran estudiades a partir de diferents vessants. En ...

    Urbanisme i arquitectura pública a la ciutat romana de Pollentia (Alcúdia, Mallorca). Segles II aC – III dC 

    Vallori Márquez, Bartomeu (Data de defensa: 2012-10-11)

    El present estudi posa en comú la recerca prèvia i fa noves propostes sobre l’urbanisme i l’arquitectura de la ciutat romana de Pollentia. A pesar de que eren diversos els edificis descoberts al llarg de les excavacions, ...

    Urdiendo Dispositivos y Nueva Política Curricular en la Construcción de Subjetividad Docente: una Investigación Dialógica con profesoras de Artes Visuales de Escuelas chilenas 

    Quintana Figueroa, Patricia Fernanda (Data de defensa: 2024-03-12)

    [spa] Esta tesis se teje desde un iniciático proceso para comprender las construcciones subjetivas de profesoras de Artes Visuales a raíz de una nueva política curricular, entendida esta como dispositivo, y junto con ello ...

    Urotelio y parasitación vesical. Estudio morfológico de la carcinogenesis por "Schistosoma haematobium". 

    Álvarez-Vijande García, Ricardo (Data de defensa: 1989-01-01)

    La génesis de los tumores de urotelio es aun hoy un capitulo desconcertante. Existe la polémica de si el carcinogeno induce su acción sobre el epitelio a través de la orina o bien incide por vía hemática a través del ...

    Usabilidad para dispositivos móviles basada en la evidencia: los cibermedios españoles 

    Jiménez Iglesias, Lucía (Data de defensa: 2018-02-23)

    La finalidad de esta investigación es elaborar un conjunto de directrices sobre experiencia de usuario (UX) que guíen el diseño de las webs de periódicos para smartphones. Para ello, el trabajo se articula en dos bloques ...

    Use of calix[4]arenes to recover the self-assembly ability of mutated p53 tetramerization domains 

    Gordo Villoslada, Susana (Data de defensa: 2008-06-30)

    Protein-protein interactions are essential in biological processes and thus, they have become very promising therapeutic targets. Nevertheless, the artificial modulation of protein complexes remains a challenge. Since most ...

    Use of chemical markers in the study of distribution range and population structure of large cetaceans = Uso de marcadores químicos en el estudio del rango de distribución y de la estructura de poblaciones de grandes cetáceos 

    Vighi, Morgana (Data de defensa: 2016-01-19)

    Cetaceans have historically been object of heavy exploitation, and are still currently subject to different threats. For conservation and management purposes, most of the large cetacean populations have been categorized ...

    The use of immersive virtual reality in neurorehabilitation and its impact in neuroplasticity 

    Matamala Gómez, Marta (Data de defensa: 2017-09-19)

    This thesis aim to test the effectiveness of an immersive virtual reality set-up by using an embodied virtual body in neurorehabilitation, specifically for motor and chronic pain disorders. More specifically, my first ...

    Usefulness of in vivo reflectance confocal microscopy and automated videomosaics in the treatment and management of skin cancers = Ús de la microscòpia confocal de reflectància in vivo i dels videomosaics automatitzats en el tractament i seguiment dels càncers cutanis 

    Yélamos i Pena, Oriol (Data de defensa: 2019-10-04)

    Skin cancer is major health problem due to its increased incidence in the last decades. Standard treatment of skin cancer is still surgery, which can be challenging to perform since most skin cancers are located in visible ...