Oncolytic adenoviruses expressing transgenes targeting the tumor stroma to enhance the antitumor efficacy 

Sostoa Pomés, Jana de (Data de defensa: 2019-05-31)

Oncolytic virus (OV)-based therapies have an emerging role in the treatment of solid tumors, involving both direct cell lysis and immunogenic cell death. Nonetheless, tumor- associated stroma limits the efficacy of oncolytic ...