Tarrés Gatius, Mireia (Date of defense: 2019-12-17)
Sub-anesthetic doses of ketamine evoke rapid and persistent antidepressant effects in treatment-resistant depressed patients through still poorly-known mechanisms. Ketamine also evokes transient ...
Ulldemolins Gómez, Marta (Date of defense: 2017-05-18)
BACKGROUND: Early and appropriate antibiotic administration has been shown to be the most effective intervention for reducing mortality in critically ill patients with septic shock and multiple organ ...
Monterrubio Martínez, Carles (Date of defense: 2016-11-17)
A new combined microdialysis – tumor homogenate method for the determination of compartmental (vascular, extra- and intracellular) SN-38 distribution in patient-derived xenografts (PDX) generated from ...
Vivas Pradillo, Daniel (Date of defense: 2018-12-14)
Bone is a highly organised and specialised connective tissue that provides a rigid, protective and supporting framework to the body. In addition to this, bone is unique in its capacity to self-regenerate ...
Fernández Noguera, Patricia (Date of defense: 2016-02-04)
HER2 positivity defines a molecular subtype of breast cancer with an aggressive biological behaviour and poor prognosis. Its pharmacological targeting with the monoclonal antibody Trastuzumab, and later ...
Medina Vives, Jordi (Date of defense: 2018-02-12)
The common scope of this thesis is the application of structural biology and biophysics to obtain novel data on nuclear proteins that modulate DNA transcription. The proper regulation and functioning ...
Garcia Diaz, Anna Isabel (Date of defense: 2018-02-16)
Parkinson’s disease is a common neurodegenerative disorder that manifests with a wide range of non-motor symptoms. Among them, cognitive impairment is present in a high proportion of patients, having a ...
Obón Santacana, Mireia (Date of defense: 2016-09-29)
Acrylamide is an organic chemical that has several important uses in industry, such as a flocculant in public water supplies, and in biomedical research. In 1994, acrylamide was classified by the ...
Ríos Hernández, Alejandra Margarita (Date of defense: 2017-01-27)
Attention-deficit hyperactivity disorder (ADHD) is one of the most common psychiatric disorders in early childhood and adolescence and its consequences can persist through adulthood. It is characterized ...