Mostrando ítems 1-10 de 17
Salomó i Prat, Ernest (Fecha de defensa: 2018-10-19)
Asymmetric hydrogenation of double bonds by means of organometallic catalysis is a powerful tool for organic synthesis; it is an efficient and simple method to produce valued chiral compounds. Among the ...
Aiguabella Font, Nuria (Fecha de defensa: 2014-02-07)
The Pauson-Khand reaction (PKR) is, formally, a [2+2+1] cycloaddition involving an alkene, an alkyne and a carbon monoxide molecule, typically mediated or catalyzed by a cobalt (0) complex. The product ...
Cabré Montesinos, Albert (Fecha de defensa: 2020-01-31)
The main contribution of this doctoral thesis has been devoted to the field of synthetic organic chemistry. The Pauson-Khand reaction (PKR) is a metal-catalyzed [2+2+1] cycloaddition between an alkyne, ...
Fuente Cebrián, Àlex de la (Fecha de defensa: 2015-01-30)
Los iminoazúcares son productos estructuralmente análogos a los azúcares convencionales en los que un nitrógeno se sitúa sustituyendo al oxígeno endocíclico. Son sustratos capaces de mimetizar la ...
Donoghue, Craig (Fecha de defensa: 2019-07-24)
The thesis consists of two main projects: a) the development of a novel strategy to gain genetic control with spatiotemporal precision, and b) the optimisation of inhibitors of the protein kinase p38α, ...
Rol Rúa, Álvaro (Fecha de defensa: 2015-12-11)
Somatostatin (SST), also known as somatotropin release-inhibiting factor (SRIF), is a 14-amino-acid peptide discovered in 1973. It is a natural hormone whose biological activity is linked to five ...
Gallen Ortiz, Albert (Fecha de defensa: 2019-02-01)
The Thesis deals with the preparation, coordination chemistry and use in asymmetric homogeneous catalysis of several optically pure P-stereogenic ligands containing a tert-butylmethylphosphino fragment. In ...
Cristóbal Lecina, Edgar (Fecha de defensa: 2014-09-29)
La hidrogenación catalítica asimétrica es uno de los métodos más importantes en síntesis orgánica. Este proceso permite acceder a importantes productos quirales a escala multigramo utilizando hidrógeno ...
Frigolé Vivas, Marta (Fecha de defensa: 2020-09-23)
[eng] Drug discovery is the process by which new drugs are found and developed into the market. Given the scope of this thesis, the term “drug” will refer to small molecules and the term “target” to ...
Matarín Morales, Joan Antoni (Fecha de defensa: 2021-12-15)
Peptides are defined as compounds that contain between two and fifty amino acids connected together by amide bonds. Inside our body, peptides are natural biological messengers that play critical roles ...