Mostrando ítems 1-10 de 61
Garcia Cabau, Carla (Fecha de defensa: 2022-05-31)
Intrinsically disordered (ID) proteins or regions are protein sequences that lack stable secondary and tertiary structures. ID proteins are particularly prone to undergo liquid- liquid phase separation ...
Szulc, Elizbieta Maria (Fecha de defensa: 2020-01-09)
Androgen receptor is a transcription factor that plays a key role in prostate cancer development and progression. Its N-terminal intrinsically disordered activation domain is an example of ill- structured ...
Solé i Codina, Laura (Fecha de defensa: 2013-12-13)
Voltage gated potassium channels (Kv) play important roles in different biological process such as generation and propagation of the nerve pulse and the cardiac action potential, promotion of insulin ...
Escobedo Pascual, Albert (Fecha de defensa: 2014-11-06)
Nedd4L is a HECT-type E3 ubiquitin ligase (it covalently binds ubiquitin molecules before transferring them to the final substrate). Ubiquitination is a posttranslational modification (PTM) that labels ...
Pujol Vidal, Maria Magdalena (Fecha de defensa: 2012-07-17)
L’enzim Carnitina palmitoïltransferasa 1 (CPT1) permet l’entrada dels àcids grassos de cadena llarga a la matriu mitocondrial per tal de ser degradats i utilitzats així com a substrat energètic. El ...
Nicolàs i Aragó, Adrià (Fecha de defensa: 2022-12-14)
[eng] L-type amino acid transporters play key roles in human physiology and are involved in several human pathologies such as primary inherited aminoacidurias (Feliubadaló et al., 1999; Torrents et al., ...
Hernaiz Llorens, Marc (Fecha de defensa: 2019-11-25)
During brain development, UNC5 receptors play a key role in controlling axonal extension through their sensing of the guidance molecule Netrin-1. The correct positioning of receptors into specific ...
Ribas Aulinas, Francesc (Fecha de defensa: 2014-10-02)
Tot i que el fetge és considerat com el principal lloc de producció del FGF21 sistèmic, sobretot en condicions de dejuni i sota control de PPARα, darrerament s’han acumulat diverses evidències que ...
Guillén Boixet, Jordina (Fecha de defensa: 2015-12-04)
Cytoplasmic polyadenylation element binding proteins (CPEBs) are a family of RNA-binding proteins essential for the translational regulation of mRNAs in various biological contexts. CPEBs recognize CPE ...
Rodríguez Carbó, Laia (Fecha de defensa: 2016-01-25)
The androgen receptor (AR) is a ligand-activated transcription factor that plays a crucial role in the correct development, differentiation, and function of male reproductive organs. Alterations in the ...