Bosch, Caroline (Date of defense: 2016-10-21)
This doctoral thesis consists in two main parts. The first part focus in the study of methodology development in order to bring modularity and diversification to compounds studied within the research ...
Bagán Polonio, Andrea (Date of defense: 2022-09-23)
The synthesis of heterocyclic organic compounds allows access to a wide arsenal of compounds with potential pharmacological activity. This Thesis is part of the field of pharmaceutical chemistry, ...
Ghashghaei, Ouldouz (Date of defense: 2017-09-26)
1. It was observed that the interaction of imines and isocyanides in the presence of a Lewis acid can lead to a variety of scaffolds including α-aminoamides, α-aminoamidines, indoles and diiminoazetidines. ...
Pérez Areales, Francisco Javier (Date of defense: 2017-07-14)
Alzheimer’s disease (AD) is the main neurodegenerative disorder and one of the most important health-care problems worldwide, because of its high prevalence and personal and economic impact. To aggravate ...
Amirthalingam, Ezhil (Date of defense: 2018-10-01)
This thesis has its main focus on developing multi-functional nanomaterials, that we called nano- and microtools through two different approaches, top-down to provide support and bottom up to give ...
Guignard, Guillaume Michel Pablo (Date of defense: 2016-06-23)
1. (R)-Phenylglycinol-derived oxazolopiperidone lactams can be converted to enantiopure open-chain amino ester scaffolds by alkaline hydrolysis of the N-Boc 2-piperidones resulting from the reductive ...
Montiel Achong, Juan Andrés (Date of defense: 2016-12-20)
Durante este trabajo de tesis doctoral se ha demostrado que las cloroacetamidas son intermedios de gran utilidad para la síntesis de heterociclos nitrogenados a través de procesos radicalarios o no ...
Puigoriol Illamola, Dolors (Date of defense: 2020-09-10)
The world is facing an unprecedented situation: soon the number of people over 60 years old will exceed the number of children, and more people at extreme old age than ever before. This is due to medical ...
Barniol Xicota, Marta (Date of defense: 2017-01-13)
L’objectiu de la present tesi doctoral consisteix en desenvolupar molècules policícliques de baix pes molecular que tinguin com a diana tres canals iònics específics: la viroporina A/M2 del virus de la ...
Coussanes, Gilhem (Date of defense: 2016-12-16)
The manuscript of this Doctoral Thesis has been divided into five main parts: a general introduction into the calyciphylline A-type alkaloids followed by three research chapters and conclude by a review ...