Coussanes, Gilhem (Date of defense: 2016-12-16)
The manuscript of this Doctoral Thesis has been divided into five main parts: a general introduction into the calyciphylline A-type alkaloids followed by three research chapters and conclude by a review ...
Abás Prades, Sònia (Date of defense: 2018-05-31)
The distinctive reactivity of isocyanides has been recognised as an advantageous characteristic for the formation of heterocyclic compounds. In the present manuscript new synthetic possibilities are ...
Pérez Janer, Ferran (Date of defense: 2018-06-01)
Among transition metals used in organic chemistry, palladium has greatly contributed to the development of modern organic synthesis. This thesis is focused on the development of novel and efficient ...
Companys Alemany, Júlia (Date of defense: 2022-07-15)
Actualment, el tractament de la malaltia d’Alzheimer (MA) és una necessitat mèdica no coberta, ja que només existeixen tres grups de fàrmacs aprovats que no són suficientment eficaços pel control de la ...
Vasilopoulou, Foteini (Date of defense: 2021-09-21)
The identification of imidazoline receptors (IR) as a novel class of receptors has posed manifold research questions regarding their pharmacological and potential therapeutic properties. Among them, ...
Lizano Gispert, Enric (Date of defense: 2020-07-24)
This doctoral thesis is focused on the investigation and development of new compounds directed to different cancer and tropical diseases targets. Drug resistance, as well in cancer as in tropical diseases, ...
Velázquez Chávez, Ana Magdalena (Date of defense: 2021-11-09)
La enfermedad del hígado graso no alcohólico es una patología sin tratamiento farmacológico específico que posee una alta prevalencia a nivel mundial, cuya etapa inicial se caracteriza por la esteatosis ...
Cosín Tomàs, Marta (Date of defense: 2017-02-28)
Epigenetic changes are currently recognized as part of the aging process and have been implicated in many age-related chronic diseases such as Alzheimer’s disease (AD). The term epigenetics includes a ...
Izquierdo Cadenas, Vanesa (Date of defense: 2021-07-21)
Factores ambientales como el ejercicio, el estrés o la dieta contribuyen a la patogénesis de enfermedades asociadas al deterioro cognitivo y al envejecimiento, modulando mecanismos de expresión génica ...
Otermin Esteras, Ane (Date of defense: 2016-11-23)
En esta Tesis doctoral, se ha puesto a punto una ruta sintética para acceder de manera rápida y eficaz, a compuestos policíclicos tipo “cinturón” que contienen dos dobles enlaces C=C casi paralelos y ...