Ara mostrant els elements 21-30 de 34
Banjer, Hamsa Jameel (Data de defensa: 2018-07-06)
Transportome alterations have been associated with oncogenesis. The loss of human Concentrative Nucleoside Transporter 1 (hCNT1) during carcinogenesis seems to be a relatively common event in tumors and ...
Ramírez Corpas, Lorena (Data de defensa: 2023-01-20)
[spa] Alrededor del 10% de los pacientes con cáncer colorrectal metastático (mCRC) presentan la mutación BRAF(V600E), mutación que está asociada a una peor respuesta al tratamiento estándar con agentes ...
Clua Villas, Anna (Data de defensa: 2023-07-17)
[eng] G-quadruplexes are non-canonical DNA structures that appear in Guanine-rich oligonucleotides. Four Guanines interact through Hoogsteen hydrogen bonds forming a tetrad which is stabilized by metallic ...
Segura Bayona, Sandra (Data de defensa: 2018-06-22)
Histone deposition during DNA replication, transcription and repair ensures the faithful maintenance of genetic and epigenetic information. The histone H3-H4 chaperone ASF1 participates in both replication ...
Raimondi, Giulia (Data de defensa: 2020-06-08)
The general goal of this thesis has been to progress oncolytic adenovirus therapy for PDAC, by the incorporation of novel preclinical models to test for patient-specific responses and the generation of ...
Sallaberry Pinto, Júlia (Data de defensa: 2019-03-22)
Local invasion is a key cell-biological event in the metastatic cascade. In response to a changing microenvironment, cancer cells may act using two main strategies of invasion: single cell invasion and ...
Delgado Martínez, Jennifer (Data de defensa: 2023-07-06)
[spa] La leucemia mieloide aguda (LMA) es una enfermedad altamente heterogénea que hoy en día continúa demandando nuevos avances terapéuticos para hacer frente a su alta mortalidad. Este trabajo se ha ...
Núñez Manchón, Estela (Data de defensa: 2020-07-16)
La viroterapia oncolítica es un tratamiento emergente basado en el uso de virus replicativos que de manera selectiva infectan células tumorales y provocan su muerte. Hasta la fecha, se han producido ...
Figueiredo, Ana Raquel Martins (Data de defensa: 2017-06-09)
Pericytes (PCs) are important regulators of the vascular development promoting vessel growth and stabilization. They have recently emerged as a therapeutic target to promote or inhibit angiogenesis. ...
Morcelle Magaña, Carmen (Data de defensa: 2017-09-19)
In most human cancers, the c-Myc transcription factor is deregulated and/or its levels are elevated, particularly in colorectal cancer (CRC). Earlier studies suggested a direct relationship between ...