Universitat Pompeu Fabra
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Radiofrequency electromagnetic fields (RF-EMF) exposure, ubiquitous in our environment due to the rise in mobile phones and wireless technology, has grown significantly in the last 30 years. This exposure is generally ...
El objetivo del estudio era identificar las exposiciones ocupacionales relacionadas con asma en empleadas de limpieza doméstica. Un estudio poblacional transversal realizado en 4,521 mujeres mostró que las empleadas del ...
Heat exposure is a growing concern for many workers around the world as climate change is causing global average temperatures to rise. Heat exposure has been linked to a number of key carcinogenic processes, but current ...
Epithelial tissues undergo extensive remodeling during embryonic development. Recent studies have revealed that, in a number of developmental processes, epithelial remodeling is associated with pulsations of individual ...
The main objectives of this work are:<br/>a) To test the predictions of suppressed-recombination chromosomal speciation models on two different lineages of mammals: rodents and rimates. Suppressed-recombination chromosomal ...
Protein-DNA interactions are indispensable players in the daily activities of cells. DNA-binding proteins regulate gene expression and are responsible of DNA replication, packaging, repair and recombination. Among them, ...
Proteins are involved in almost all cell processes, with physical interaction between them being key to their function and dictated by its 3D structure. Hence, the study of protein-protein interactions and protein-protein ...
Tumors are composed of fast-growing cells that become malignant under selection of biological functions needed for cancer development. In this thesis, I intend to uncover the basic evolutionary principles underlying cancer ...
La música està present en totes les cultures. Tot i tenir les mateixes habilitats auditives, la manera en la què experimentem la música depèn del context cultural, la música que escoltem en el dia a dia o si hem rebut ...
The vast diversity of life on Earth develops from relatively uniform beginnings via self-organised movements occurring between groups of cells. Whilst the variety of shapes resulting from morphogenesis is boundless, the ...
The role of epistasis – inter-dependent contributions of alleles to fitness – in shaping genetic variation within and between populations is an important question in evolutionary biology with significant implications for ...
Models of speech perception differ in the nature of the relationship between speech perception and production. Whether speech perception and production processes are based on a common representations ̶ the articulatory ...
Per tal d'estudiar la relació complexa entre l'estructura d'un circuit genètic i la seva funció, ens centrem en estudiar dues proprietas: la seva capacitat evolutiva i la seva multi-functionalitat. Primer, fins a quin punt ...
Proteins are indispensable players in virtually all biological events. The functions of proteins are determined by their three dimensional (3D) structure and coordinated through intricate networks of protein-protein ...
In this thesis, I present an alternative, cloning-free method for the generation of endogenous fluorescent reporters in the nematode Caenorhabditis elegans. I demonstrate that Nested CRISPR is an efficient method that can ...
Microbiome studies have burgeoned in the last few decades, largely thanks to the innovations in high throughput sequencing, affording researchers the opportunity to categorize nearly the entirety of the microbial population ...
Orexin-A and orexin-B (also known as hypocretin-1 and hypocretin-2) are two neuropeptides exclusively expressed by a small subpopulation of neurons located within the lateral hypothalamic area. These neuromodulators were ...
The origin of eukaryotic compartmentalization stands as a major conundrum in biology. Current evidence indicates that the last eukaryotic common ancestor (LECA) already possessed many eukaryotic hallmarks, including a ...
Post-transcriptional networks control multiple aspects of neuronal biology and their deregulation has been associated with human neurological disorders. This thesis focuses on regulation at the level of pre-mRNA splicing, ...
Successful chromosome segregation is crucial for the survival of a cell and to avoid diseases such as cancer. Anaphase bridges are a type of segregation defect that can arises from structurally compromised chromosomes. ...
