Browsing Programa de Doctorat en Biomedicina by Title

Now showing items 1292-1296 of 1296

Zeb1, un gen implicat en la repressió transcripcional de l'E-Cadherina durant la transició epiteli-mesènquima. Caracterització del mecanisme de regulació de la seva expressió

Guaita Esteruelas, Sandra (Date of defense: 2005-09-21)

Durant la transició Epiteli-Mesènquima (TEM), el factor de transcripció Snail reprimeix la transcripció de l'E-cadherina unint-se a les caixes E presents en el promotor d'aquest gen.<br/>Les cèl·lules que expressen Snail ...

Zebrafish lateral line system: The roles of Eya1 in migrating primordium and Notch signaling in hair cell development and regeneration

Wibowo, Indra (Date of defense: 2011-07-04)

The purpose of this thesis is to introduce and demonstrate several biological processes or phenomena using posterior lateral line system of zebrafish as a model. The first part of this work focuses on the highly dynamic ...

Zinc homeostasis and disease : Impact on breast cancer progression and infection severity

Vogel González, Marina (Date of defense: 2021-09-03)

Zinc is an essential trace element with structural, catalytic and signaling roles in our body. At cellular level, zinc homeostasis participates in fundamental functions such as cell proliferation, migration, differentiation ...

ZRF1-mediated transcriptional regulation in acute myeloid leukemia

Demajo Meseguer, Santiago (Date of defense: 2014-02-21)

Acute myeloid leukemia (AML) is frequently linked to epigenetic abnormalities and deregulation of gene transcription, which lead to aberrant cell proliferation and accumulation of undifferentiated precursors. ZRF1, a ...

β-catenin fluctuates in mouse ESCs and is essential for Nanog-mediated reprogramming of somatic cells to pluripotency

Pedone, Elisa (Date of defense: 2014-12-16)

Mouse embryonic stem (ES) cells derived from the inner cell mass of the blastocyst can be maintained in culture, under pluripotent conditions, using Serum+LIF medium. However, it has been published that the minimal combination ...