Universitat Pompeu Fabra
Now showing items 890-909 of 1298
Bloquejar la via PD-1/PD-L1 ha sorgit com una estratègia prometedora per a restaurar la resposta immune efectora en individus infectats amb el virus de la immunodeficiència humana (VIH). Malgrat l’extensa recerca duta a ...
El objetivo general de esta tesis es estudiar la frecuencia (prevalencia, incidencia y persistencia) de los pensamientos y conductas suicidas entre los universitarios españoles, así como aportar evidencia sobre su asociación ...
Proteins and protein interactions are involved in virtually all processes of life. Here we study interactions between globular domains and short linear motifs, which form a small interface ideal for transient interactions. ...
PURPOSE: To determine the management performance indicators most frequently utilized in academic radiology departments in the United States. MATERIALS AND METHODS: This investigation met the criteria for an exemption from ...
Persistent organic pollutants (POPs), bisphenol A (BPA) and pthalates may increase the risk of respiratory infections and allergic diseases in infants and the effects might last until, at least, adolescence. Cytokines and ...
This thesis explores technical factors influencing brain PET quantification, developing brain PET harmonization framework, assessing Centiloid robustness as a clinical biomarker, and evaluating the associations between ...
Although the well established efficacy of methadone maintenance treatment (MMT) in the opioid dependence disorder, there is a group of patients that are poor responders. The study of the influence of methadone pharmacodynamics ...
The protein phosphatase calcineurin (Cn), together with its substrates, the transcription factors NFATc, play an essential role in several physiological processes of vertebrates, such as the immune response, angiogenes ...
Under very specific pressures, evolution turns extremely convergent, to the extent that distantly-related organisms show highly similar morphological, physiological and behavioral adaptations. Life into the perpetual ...
This thesis aims to study the determinants and trajectories of cognitive development, as well as the role of physical activity on cognitive and brain development in children aged 4 to 14 years old. We used data from two ...
Physical inactivity is a hallmark of Chronic Obstructive Pulmonary Disease (COPD), which relates to outcomes relevant for patients and healthcare providers. Despite its importance, no patient reported outcome (PRO) instrument ...
Physical inactivity is a major public health problem, and evidence suggests that it is a contributing factor in numerous chronic diseases and conditions. Along with smoking and poor dietary habits, physical inactivity is ...
The complete blood count (CBC) is one of the most commonly performed test due to its clinical utility, versatility and safety. Thus, there are well established consensus rules to review a CBC through the peripheral blood ...
Cocaine use profoundly disrupts the neuronal circuits that regulate reward processing, motivation and decision making, resulting in long-lasting neuroplastic adaptations in the mesocorticolimbic system. The endocannabinoid ...
The mechanical dependence of transformation and metastasis is an emerging field, but the role of mechanosensitive channels has been largely omitted. This thesis focuses on the roles played by the mechanosensitive ion ...
Fenómenos de fusión celular heterotípica están asociados con regeneración de tejidos en mamíferos. La reprogramación de células somáticas a estadios de células madre progenitoras o pluripotentes, ...
Aquesta tesi té per objectiu ampliar el coneixement sobre la pobresa energètica i la seva relació amb la salut a la Unió Europea i a Barcelona, tenint en compte les desigualtats socials. Per tal d’assolir aquest objectiu ...
Las ciudades están densamente pobladas y ofrecen una diversidad cultural, religiosa, étnica, y de costumbres. Suele estar dividida por demarcaciones socioeconómicas. Las desigualdades en el desarrollo infantil temprano son ...
Polycomb group (PcG) proteins are transcriptional repressors that control cell identity and development. In mammals, at least five different Cbx prorteins are believed to associate with the core Polycomb repressive complex ...
L'adenocarcinoma ductal pancreàtic (PDAC) és un dels càncers més letals. Per tal de millorar el diagnòstic precoç, s'estan investigant les etapes inicials de la formació del càncer, com és el cas de les lesions preneoplàstiques, ...
