Atcher Ubiergo, Joan (Date of defense: 2015-07-28)
Dynamic combinatorial chemistry proposes the creation of a library of compounds (dynamic combinatorial library, DCL) inter-connected through reversible chemical processes. The concentrations in a DCL ...
Balaceanu, Alexandra (Date of defense: 2018-12-12)
1. The Force Field Accuracy Problem. The utility and applicability of MD simulations to model biomolecular systems goes only as far as its ability to sufficiently sample the conformational space and ...
Salmatonidis, Apostolos (Date of defense: 2019-09-30)
Exposure to nanoparticles has been associated with adverse effects on human health. When the exposure route is inhalation, nanoparticles can cause pulmonary inflammation which may be more severe than ...
Alagia, Adele (Date of defense: 2015-12-11)
To direct post-transcriptionally gene silencing, RNAi machinery exploits the formation of base pairs between the loaded guide strand and the complementary mRNA. The Ago2 protein is the “slicer” effector ...
Mendive Tapia, Lorena (Date of defense: 2017-02-17)
In the present thesis we have investigated the development of new methodologies for the selective and straightforward chemical modification of Trp amino acid either alone or in peptides. In the first ...
Bazyaran, Fatemeh (Maryam) (Date of defense: 2019-04-01)
The main objective of this research work was to produce environmentally friendly cermets coatings, Ni and Co free matrix, alternative to conventional WC- Co, by thermal spray processes. WC-Co cermets ...
Font Ingles, Joan (Date of defense: 2017-06-09)
Pain is one of the main medical problems that in several cases results into a chronic disease with limited effective treatment, thus the discovery of new drugs to fight against constitutes a big challenge ...
Mayans Ayats, Júlia (Date of defense: 2018-12-14)
This PhD thesis has been developed in the Molecular Magnetism Group of the University of Barcelona. As its name indicates, the Molecular Magnetism Group is mostly interested in the magnetic study of ...
Puig Gomà-Camps, Eduard (Date of defense: 2019-06-20)
Alzheimer’s disease (AD) is the most common form of dementia. It was first described in 1906 by Alois Alzheimer. Later on, in 1984 George Glenner and Colin Masters isolated the amyloid-beta (Aβ) peptide ...
Velázquez Gómez, Miquel (Date of defense: 2019-10-21)
Dust has been used as a surrogate of indoor organic contamination for several decades. Their concerns for human health include from sensitization effects such as allergies to toxic effects derived ...